Document Type

Poster

Publication Title

Northrop Grumman Engineering & Science Student Design Showcase

Abstract

Is decreased microtubule stability a key mechanism for tauopathies? Do Tau mutations cause developmental defects? Here, we show disease-associated Tau mutations induce developmental defects. Further, we test the effects of modulating microtubule stability through genetic deletion of the key stability regulator, ptrn-1

Advisor

Melissa A. Borgen

Publication Date

4-25-2025

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