Document Type
Poster
Publication Title
Northrop Grumman Engineering & Science Student Design Showcase
Abstract
Mild traumatic brain injury (mTBI), particularly from repetitive sublethal blasts, is linked to progressive neurodegeneration and cognitive decline. GABAergic neurons are especially susceptible, yet mechanistic insights remain limited in mammalian models. Caenorhabditis elegans, with its conserved neuroanatomy and genetic tractability, enables high-resolution analysis of neural damage. This study uses a GFP reporter strain to visualize GABAergic damage post-blast, establishing a scalable model for mTBI pathophysiology.
Advisor
Timothy A. Crombie
Publication Date
4-25-2025
Recommended Citation
Scarpino, Pia F., "Pressure induced GABAergic neuron damage in C. elegans" (2025). Biomedical Engineering and Sciences Student Publications. 16.
https://repository.fit.edu/bces_student/16