Chemistry and Chemical Engineering Student Publications
Document Type
Poster
Publication Title
Northrop Grumman Engineering & Science Student Design Showcase
Abstract
Cyanines are highly conjugated molecules with useful properties, such as ease of aggregation and fluorescence. In this project, they were incorporated into an acrylamide-based nanogel made through organic synthesis to exploit these properties for controlled drug delivery. Exposing the nanogel to nearinfrared (NIR) light causes it to react with reactive oxygen species (ROS), forming an unstable intermediate. The intermediate splits into two fragments, releasing the nanogel's cargo.1 The cargo, temozolomide, is an alkylating agent which can be used to disrupt the DNA of cancer cells.
Advisor
Nasri Nesnas
Publication Date
4-24-2026
Recommended Citation
Clary, Presley, "Photochemical Activation of Cyanine-Based Nanogels for Controlled Drug Delivery" (2026). Chemistry and Chemical Engineering Student Publications. 39.
https://repository.fit.edu/cce_student/39